Dr Festus Osho Taiwo
Email Address: oftaiwo@oauife.edu.ng: oftaiwo@gmail.com
Name: Dr Festus Osho Taiwo
Staff: Academic Staff
Rank in the department: Senior Lecturer
Short Bio, Academic, and Research Activities:
A Senior Lecturer at Department of Chemistry, Obafemi Awolowo University, Ile-Ife. Nigeria. As an organic Chemist, my research interest is in the design and development of new therapeutic agents by the synthesis of biologically active heterocyclic compounds that may be derivatized to generates an array of new compounds which may be screened for their pharmacological activity, in vivo or in vitro for the purpose of identifying a lead molecule which can be further optimized by synthetic modification. My research interest in the design of heterocyclic drug like molecules has enabled me to develop advanced skills in synthetic organic methodology as well as spectroscopic techniques.
Academics
(i) Bachelor of Science in Education 2001
(ii) Master of Science Chemistry 2007
(iii) Doctor of Philosophy in Chemistry 2016
Research Activities
▪ Synthesis of various Quinoxaline derivatives with antimicrobial, anti-bacterial and
neuropharmacological activities
▪ Design, Synthesis of phthalimides Derivatives with biological activities.
▪ Synthesis of 2-phenylglyoxylic acid derivatives with Antibacterial and Anti-inflammatory Activities.
▪ Antibacterial, Antifungal and Phytochemical Analysis of crude extracts from the
plants
Office/Room Number:
Area of Specialization: Organic Chemistry and Medicinal Chemistry
Current Research Projects for Postgraduate Students:
1.Design, Synthesis, Reactions and Biological activities of 5-(7-bromo-2-
chloropyrido[2,3-b] pyrazin-3-yl)-1-phenyl-1H-pyrazole-3-carbaldehyde
2. Design, Synthesis, Reactions and Biological activities of 5-(2-chloropyrido[2,3-
b] pyrazin-3-yl)-1-phenyl-1H-pyrazole-3-carbaldehyde
3. Design, Synthesis, Reactions and Biological activities of 1-(4-aminophenyl)-5-
(2-chloropyrido[2,3-b] pyrazin-3-yl)-1H-pyrazole-3-carbaldehyde
4. Design, Synthesis, Reactions and Biological activities of (Z)-2-(1Hbenzo[d]imidazole-2-yl)-N’-4-chlorobenzylidenebenzohydrazide
5. Design, Synthesis, Reactions and Biological activities of (S)-3-((3-oxo-3,4-
dihydroquinoxalin-2-yl)amino)-4-phenyl-3,4-dihydrobenzo[e][1,2]oxazepine1,5 dio1
List of Selected Publications (with DOI Number or a Hyperlink):
- O. Taiwo, C. A. Obafemi, E. M. Obuotor and I. J. Olawuni (2021). Synthesis of some phenylisoindoline-1,3-diones and their acetylcholinesterase and butyryl
cholinesterase inhibitory activities. Journal of Pharmaceutical Research
International. 33(51B): 194-201 (DOI: 10.9734/JPRI/2021/v33i51B33539)
F. O. Taiwo, C. A. Obafemi, E. M. Obuotor and I. J. Olawuni (2021) Synthesis of
Sulfanoquinoxaline-2,3-Dione Hydrazones Derivatives as a Selective
Inhibitor for Acetylcholinesterase and Butyryl Cholinesterase. Journal of
Applied Life Sciences International. 24(8): 8-16 (DOI:10.9734/JALSI/2021/v24i830252)
Festus O. Taiwo, Craig A. Obafemi and David A. Akinpelu (2021). Synthesis of Some
Quinoxaline sulfonamides as a potential Antibacterial agent. Journal of Pharmaceutical Research International. 33(51B): 116-132 (DOI: 10.9734/JPRI/2020/v33i51B33521)
F. O. Taiwo, C. A. Obafemi, E. M. Obuotor and I. J. Olawuni (2021), Design, Synthesis and Biological Activities of some phthalimides Derivatives. Current Journal of Applied Science and Technology. 40(33): 50-56 (DOI: 10.9734/CJAST/2021/v40i3331563)
F. O. Taiwo, C.A. Obafemi and D.A. Akinpelu (2021) Design, Synthesis, reactions and Antibacterial properties of 2-hydrazinyl-3-methyl-6-nitroquinoxaline Derivatives. Journal of Advances in Microbiology. 21(11): 115-127 (DOI: 10.9734/JAMB/2021/v21i1130408)
Festus O. Taiwo, David A. Akinpelu and Craig A. Obafemi (2021). Recent Advances on the Synthesis, Reactions and Evaluation of the Pharmacological Properties of
Quinoxaline, Quinoxaline-2-One and Quinoxaline-2,3-Dione. International
Research Journal of Pure and Applied Chemistry 22(8) 35-54 (DOI:10.9734/IRJPAC/2021/v22i830427)
F. O. Taiwo, C. A. Obafemi, D. A. Akinpelu and T. O. Iyiola (2021), Design, Synthesis and Antibacterial Activity of some 3,6-Dimethlyquinoxaline-2-Hydrazone
Derivatives. Journal of Applied Life Sciences International 24 (6)48-61 (DOI: 10.9734/JALSI/2021/v24i630244)
Taiwo, F. O and Craig A. Obafemi (2021), Design, green synthesis and reactions of 2,3-dioxo-1,2,3,4- tetrahydroquinoxaline-6-Sulfono-hydrazide derivatives.
International Journal of Physical Sciences 16 (14) 123-137 (DOI: 10.5897/IJPS2016.4548).
Taiwo, F. O, Olaoluwa Oyedeji, & Moyosore T. Osundahunsi (2019). Antimicrobial and Antioxidant properties of kaempferol-3-O-glucoside and 1-(4-Hydroxyphenyl)-3- phenylpropan-1-one isolated from the leaves of Annona muricata Linn. Journal of Pharmacy Research International 26 (3) 1-13(DOI: 10.9734/JPRI/2019/v26i330138)
Taiwo, F. O, E.M. Obuotor, I. J. Olawuni, D.A. Ikechukwu and T.O. Iyiola (2017). Design, Synthesis and Biological Evaluation of Some Novel 3-methyl quinoxaline-2-
hydrazone Derivatives. Organic Chemistry Current Research 6:181, 1-6 ( doi: 10.4172/2161-0401.1000181)
Google Scholar and/ Scopus Link(s):
Google Scholar: https://scholar.google.com/citations?user=iFjhcGIAAAAJ
Scopus: https://www.scopus.com/redirect.uri?url=https://orcid.org/0000-0003-2204-6782&authorId=35075146100&origin=AuthorProfile&orcId=0000-0003-2204-6782&category=orcidLink
http://www.scopus.com/inward/authorDetails.url?authorID=35075146100&partnerID=MN8TOARS