Dr. T.O. Olomola

OLOMOLA, Temitope O., PhD., MNYA

Rank: Senior Lecturer, Department of Chemistry

Office: Room 216A (Second Floor, White house), Department of Chemistry, OAU, Ile-Ife.

Email: tolomola@oauife.edu.ng; oloms2002@yahoo.co.uk

Scholar link: Google Scholar

Profile:

Temitope Olomola obtained his B.Sc (Hons) Chemistry and M.Sc (Organic Chemistry) from University of Ibadan, Ibadan, Nigeria in 2002 and 2005, respectively. With an M.Sc degree in natural product Chemistry, he proceeded to the Obafemi Awolowo University, Ile-Ife, where he obtained an M.Phil in Organic Synthesis. He later moved to Rhodes University, Grahamstown, South Africa, where he obtained a PhD in Synthetic Organic Chemistry in 2012. Dr. Olomola joined the services of the Chemistry Department, Obafemi Awolowo University, Ile-Ife, in 2006.  

Dr. Olomola has been involved in the development of Science through various community engagement initiatives. Effort in this direction led to him receiving the 2011 Rhodes University Engaged Student of the year Award and the Investec Rhodes Top 100 Award, Community Engagement (2011). In 2005, Dr. Olomola was admitted as a member of the prestigious Nigerian Young Academy (NYA) and in 2017 he became the President of the Academy. He has served in different capacities in the University, such as Chemistry Coordinator for the Predegree Programme (2013-2016), elected member of the University Senate (2013-2017) and elected member of the University Appointment & Promotions Committee (2016-2017).

Area of Specialisation / Research Interest:

  1. Heterocyclic Compounds with Medicinal Potential: Applications of the Baylis-Hillman reaction in the synthesis of biologically active heterocyclic systems, as potential HIV-1 inhibitors.
  2. Kinetic-mechanistic studies of organic reaction mechanisms and computer modelling.
  3. Application of iodine in organic synthesis.

Selected Publications:

(i) Olomola, T.O., Klein, R., Mautsa, N., Sayed, Y. and Kaye, P.T. (2013), ‘Synthesis and Evaluation of Coumarin Derivatives as Potential Dual-action HIV-1 Protease and Reverse Transcriptase Inhibitors’ Bioorganic & Medicinal Chemistry, 21, 1964-1971.

(ii) Olomola, T.O., Akinpelu, D.A. and Obafemi, C.A. (2013), ‘Microwave-assisted Synthesis and Antibacterial Activity of Some Quinazolinone Derivatives.’ Journal of Pharmacy Research, 6, 633-637.

(iii) Olomola, T.O., Klein, R. and Kaye, P.T. (2014), ‘Synthesis of Cinnamate Ester-AZT Conjugates as Potential Dual-action HIV-1 Integrase and Reverse Transcriptase Inhibitors.’ Tetrahedron, 70, 9449-9455.

(iv) Faridoon, Olomola, T.O., Tukulula, M., Klein, R. and Kaye, P.T. (2015), ‘Strong Base- or Acid-mediated Chemoselectivity Shifts in the Synthesis of 2H-Chromene or Coumarin Derivatives from Common Baylis-Hillman Adducts’. Tetrahedron, 71, 4868-4873.

(v) Ceban, V., Olomola, T.O., Meazza, M. and Rios, R. (2015), ‘Highly Diastereoselective Synthesis of Spiropyrazolones’. Molecules, 20, 8574-8582.

(vi) Manyeruke, M.H., Olomola, T.O., Majumder, S., Abrahams, S., Isaacs, M., Mautsa, N., Mosebi, S., Mnkandhla, D., Hewer, R., Hoppe, H.C., Klein, R., and Kaye, P.T. (2015), ‘Synthesis and Evaluation of 3-Hydroxy-3-phenylpropanoate Ester‒AZT Conjugates as Potential Dual-action HIV-1 Integrase and Reverse Transcriptase Inhibitors’ Bioorganic & Medicinal Chemistry, 23, 7521-7528.

(vii) Faridoon, Olomola, T.O., Klein, R. and Kaye, P.T. (2016), ‘Application of Baylis-Hillman Methodology in the Direct Construction of Chromone Derivatives’. Tetrahedron, 72, 392-395.